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C7orf24

WebAug 17, 2009 · T he putative protein C7orf24 is encoded by Homo sapiens chromosome 7 open reading frame 24 (GenBank accession number: NM_024051). The C7orf24 protein … WebGamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is encoded by the gene C7orf24, and the enzyme participates in the gamma-glutamyl cycle.

Human Gene GGCT (uc022abe.1)

WebJun 1, 2012 · Chromosome 7 open reading frame 24 (C7orf24), which was identified by proteome analysis, is upregulated in various types of cancer and is associated with cellular proliferation. However, in vivo... WebJan 5, 2024 · C7orf24 encodes γ-glutamylcyclotransferase (GGCT), an enzyme involved in glutathione metabolism that catalyzes the generation of 5-oxoproline and free amino acids from γ-glutamyl peptides . binley business park google maps https://fatfiremedia.com

Dissertations / Theses:

WebSep 22, 2016 · Background Chromosome 7 open reading frame 24 (C7orf24) was originally identified as a highly expressed protein in various types of cancer, and later shown to be a γ-glutamylcyclotransferase (GGCT). GGCT depletion in cancer cells has anti-proliferative effects in vitro and in vivo, and it is therefore considered a promising candidate as a … WebAug 6, 2010 · A set of 123 primary breast tumors and matched normal tissue was analyzed by two-dimensional (2D) gel electrophoresis, and a novel protein, C7orf24, was identified as being upregulated in cancer... WebNov 1, 2011 · Human chromosome 7 ORF 24 (C7orf24) has been identified as a tumor‐related protein, and shown to be a γ‐glutamyl cyclotransferase. In the current study, we characterized the promoter region of the human C7orf24 gene to explore the transcriptional regulation of the gene. We revealed that the human C7orf24 promoter is a … binley chip shop opening times

A novel tumor‐related protein, C7orf24, identified by …

Category:A novel tumor‐related protein, C7orf24, identified by proteome ...

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C7orf24

Involvement of cancer biomarker C7orf24 in the growth of …

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C7orf24

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WebJun 1, 2012 · Immunohistochemical analysis revealed that C7orf24 levels were significantly reduced within tumor tissues collected from anti-C7orf24 siRNA-administered mice, indicating that the knockdown of C7orf24 induced cytotoxicity in tumor tissue. In conclusion, these data show for the first time that knockdown of C7orf24 prevents tumor growth in … WebSep 1, 2009 · C7orf24 was first identified as a 21-kDa cytochrome c-releasing factor detected in the cytosolic fraction of human leukemia U937 cells after treatment with geranylgeraniol. C7orf24 protein was...

WebAug 8, 2008 · The hypothetical protein C7orf24 has been implicated as a cancer marker with a potential role in cell proliferation. We have identified C7orf24 as γ-glutamyl cyclotransferase (GGCT) that catalyzes the formation of 5-oxoproline (pyroglutamic acid) from γ-glutamyl dipeptides and potentially plays a significant role in glutathione …

WebC7orf24 is currently registered in the protein database as a hypothetical protein with unknown function. The homologs of C7orf24 in other animals have also been registered … WebAug 8, 2008 · The hypothetical protein C7orf24 has been implicated as a cancer marker with a potential role in cell proliferation. We have identified C7orf24 as γ-glutamyl …

WebBackground: Up-regulation of the expression of the gene C7orf24, encoding γ-glutamyl cyclotransferase, is a common event in cancers derived from various tissues, but its involvement in osteosarcomas (OS) has not yet been demonstrated. Materials and methods: The expression of C7orf24 was analyzed in human OS cell lines and primary tumor …

WebFeb 1, 2007 · C7orf24 was originally identified as a bladder cancerspecific protein, and is now recognized as a good candidate for a diagnostic marker [1, 4]. Similarly, we also … dachsund in a dishwasherWebWe have identified C7orf24 as γ-glutamyl cyclotransferase (GGCT) that catalyzes the formation of 5-oxoproline (pyroglutamic acid) from γ … binley chip shopWebHuman chromosome 7 open reading frame 24 (C7orf24)/γ-glutamyl cyclotransferase has been suggested to be a potential diagnostic marker for several cancers, including … binley bridge coventryWebNov 1, 2008 · We have identified C7orf24 as γ-glutamyl cyclotransferase (GGCT) that catalyzes the formation of 5-oxoproline (pyroglutamic acid) from γ-glutamyl dipeptides … binley business park coventry cv3 2tqWebWe have identified C7orf24 as -glutamyl cyclotransferase (GGCT),2a poorly studied enzyme in the -glutamyl cycle. -glutamyl cycle involves the synthesis of glutathione and its utilization in the uptake of amino acids, particularly in the renal tubule and across the blood-brain barrier in the cho- roid plexus in the brain (4, 5) (Fig. 1). dachsund on laptopWebDue its ability to provide a global snapshot of kidney physiology, urine has emerged as a highly promising, non-invasive source in the search for new molecular indicators of disease diagnosis, prognosis, and surveillance. In particular, proteomics represents an ideal strategy for the identification of urinary protein markers; thus, a urinomic approach could also … binley court coventryWebProteome analysis of bladder cancer with narrow-range pH 2-DE has identified a novel protein on chromosome 7 encoded by ORF 24 (C7orf24) as one of the highly expressed proteins in cancer cells. C7orf24 is currently registered in the protein database as a hypothetical protein with unknown function. binley chippy song