WebCapmatinib, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor INC280 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. Web瑞禧生物提供科研级mPEG-b-PDMAPS 聚乙二醇单甲醚-b-甲基丙烯酰氧乙基-N,N-二甲基丙磺酸盐,我们一直致力于研发纳米靶向科研产品以满足国内广大科研院校及其他相关科研单位的需求。mPEG-b-PDMAPS 聚乙二醇单甲醚-b-甲基丙烯酰氧乙基-N,N-二甲基丙磺酸盐试剂不能用于人体治疗、药物开发、和其他商业用途。
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WebINCB28060, also known as Capmatinib and INC280, is a novel and ATP-competitive inhibitor of c-Met with IC50 of 0.13 nM. c-Met, also named as hepatocyte growth factor receptor … WebReceptor Insulinolikog faktora rasta 1 (IGF-1) jest protein ćelijske površine koji je kod ljudi kodiran genom IGF-1 sa hromosoma 15.To je transmembranski receptor koji se aktivira hormonom koji se zove insulinoliki faktor rasta 1 i srodnim hormonom zvanim IGF-2.Pripada velikoj klasi tirozin-kinaznih receptora. Ovaj receptor posreduje u efektima IGF-1, koji je … cabinets by cantu
INCB28060 CAS:1029712-80-8 C-Met inhibitor,ATP ... - BioCrick
WebSep 16, 2024 · A high throughput apoptosis assay using 3D cultured cells was developed with a micropillar/microwell chip platform. Live cell apoptosis assays based on fluorescence detection have been useful in high content screening. To check the autofluorescence of drugs, controls (no caspase-3/7 reagent in the assay) for the drugs are necessary which … WebMar 12, 2015 · Other Name: INCB28060. Biological: bevacizumab bevacizumab: 10 mg/kg IV every 2 weeks. Patients with unresectable GBM will be given 15 mg/kg IV every 4 weeks. Other Name: Avastin. Outcome Measures. Go to Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations … WebINCB28060, a novel inhibitor of c-MET kinase. INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10,000-fold selectivity over a … cls mayenne